New analysis software brings cutting-edge bioinformatics tools to bench scientists
ASHLAND, Ore.–(BUSINESS WIRE)–FlowJo, LLC, a bioinformatics and data analysis company with 19+ years experience in software for analyzing single-cell data, launched SeqGeq today, a desktop application that gives bench scientists the ability to quickly and efficiently analyze single-cell omics data.
SeqGeq offers a powerful set of tools that help researchers rapidly identify subpopulations of cells within their samples based on a variety of genes and synthetic parameters that combine hundreds of genes, compare and contrast these clusters to identify differentially-expressed genes or pathways of interest, and generate publication-ready heatmaps and figures using a powerful drag-and-drop layout editor. SeqGeq is platform-agnostic and accepts a wide variety of data types, including scRNA-seq, RNA-Seq, or microarray data.
“Single-cell NGS is a powerful tool, but exploring and analyzing the often large and complex datasets generated in these experiments isn’t trivial,” says Courtney Nadeau, Genomics Product Manager at FlowJo, LLC. “These analyses have needed complex software packages with specific hardware requirements and are usually hidden behind a command line. SeqGeq breaks this model by enabling everyone, regardless of their bioinformatics skills, to employ the same high-impact tools to explore their data, but with an intuitive drag-and-drop interface and immediate feedback.”
“Engineering SeqGeq as a desktop application has required us to re-think how we implement traditional algorithms like PCA, LDA, and t-SNE,” says Josef Spidlen, Senior Bioinformatics Software Engineer at FlowJo, LLC. “Single-cell omics data are usually sparsely populated and have a huge number of parameters. We found that standard approaches to dimensionality reduction would run for hours on a normal laptop, but that wasn’t compatible with the iterative, hands-on style of analysis that researchers wanted. Through extensive optimization, we’ve cut the processing time by an order of magnitude, and SeqGeq can complete these tasks in a few minutes rather than hours, allowing biologists to drive their analysis in real time.”
SeqGeq by FlowJo, LLC is available now. For more information about SeqGeq, to request a free trial license, or to get up-to-date training on single-cell data analysis, visit www.flowjo.com.
About FlowJo, LLC
FlowJo, LLC is a privately owned life sciences software company in Ashland, Oregon. Based on technology developed at Stanford, the company was founded in 1997 and provides the leading analysis platform for single-cell flow cytometry analysis. Their software innovations enable collaboration, discovery, high-throughput analysis, and data leadership in single-cell biology. For more information, see www.flowjo.com.
Contacts
FlowJo, LLC
Caitlin Farquhar
caitlinf@flowjo.com